Wednesday, October 6, 2010

People at risk

A number of non-modifiable increase the risk of suffering from breast cancer.

These elements may allow doctors to determine who might benefit most from screening and preventive measures.

Key risk

* Female: Less than 1% of breast cancer cases occur in men, and they generally have more than 60 years.

* Age: The disease rarely affects women under 30 years. About 85% of cases occur in 50 years or more2. The more a woman gets older, the risk of suffering from breast cancer increases.

* Family history: Having a mother, sister or daughter suffering from breast cancer or ovarian cancer increases the risk of developing it. 5% to 10% of breast cancers are caused by an abnormality transmitted by heredity. Major susceptibility genes for breast cancer (and ovarian) are named BRCA1 and BRCA2. Normally, these genes protect against cancer. If they are defective, they can no longer fulfill their duties. There are tests to see if a woman from a family at risk is itself carries a mutation in one of these genes.

* Personal history: Having already had cancer in one breast increases the risk of a second cancer is formed.

* Have an injury risk to the breast (diagnosed in a biopsy). Women who have an injury risk, such as atypical ductal epithelial hyperplasia or lobular carcinoma in situ, are more likely to be suffering from breast cancer one day.

Note. Note that the cyst within a lesion is not at risk. It does not increase the risk of breast cancer.

Other risk

* Radiotherapy treatments: We know that women who have undergone high-dose radiation to the chest (X-ray high-intensity) have a higher risk of suffering from breast cancer, especially if radiation has been over the age 30.

* Nulliparity or late pregnancy: The fact of not having children or having just given birth after age 30.

* Increased exposure to natural estrogens: The early onset of first menstruation (before age 12 years) or late menopause (after age 55 years).

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